Les publications récentes

Nihil morati post haec militares avidi saepe turbarum adorti sunt Montium primum, qui divertebat in proximo, levi corpore senem atque morbosum, et hirsutis resticulis cruribus eius innexis divaricaturn sine spiramento ullo ad usque praetorium traxere praefecti. Martinus agens illas provincias pro praefectis aerumnas innocentium...

Arsic D, Keenan J, Quan QB, Beasley S.Pediatr Surg Int. 2003 May 27Christchurch School of Medicine, Department of Paediatric Surgery, Christchurch Hospital, 4710, Private Bag, Christchurch, New Zealand. Sonic hedgehog (Shh) protein is a signalling molecule that is important for defining patterning in the development...

Spilde T, Bhatia A, Ostlie D, Marosky J, Holcomb G 3rd, Snyder C, Gittes G.
Department of Surgery, The Laboratory for Surgical Organogenesis, Children's Mercy Hospital, Kansas City, MO.
J Pediatr Surg. 2003 Mar;38(3):465-8.

Background/Purpose

Many theories of the pathogenesis of esophageal atresia with tracheoesophageal fistula (EA/TEF) have been proposed, but no specific mechanism has been demonstrated. The authors previously reported data suggesting a respiratory origin of the fistula tract in the rat model and in humans. Sonic hedgehog (Shh) "knockout" mice have the VACTERL association, and thus it was hypothesized that defects in Shh signaling may exist in the human neonatal EA/TEF fistula tract.